Prostate Cancer Therapeutics Market

The report “Prostate Cancer Therapeutics Market to 2019 – Rising Prevalence and Strong Uptake of Recent Approvals to Drive Robust Growth to 2019″ by GBI Research is now available at RnRMarketResearch.com. Contact sales@rnrmarketresearch.com with Prostate Cancer Therapeutics Market to 2019 – Rising Prevalence and Strong Uptake of Recent Approvals to Drive Robust Growth to 2019 in subject line and your contact details to purchase this report or get your questions answered.

The collection of ‘Cancer Therapeutics’ market research reports has a new addition of “Prostate Cancer Therapeutics Market to 2019 – Rising Prevalence and Strong Uptake of Recent Approvals to Drive Robust Growth to 2019” on RnRMarketResearch.com. The Pharmaceutical Report – “Prostate Cancer Therapeutics Market to 2019 – Rising Prevalence and Strong Uptake of Recent Approvals to Drive Robust Growth to 2019”. The recent approval of a number of highly effective drugs, including Zytiga and Xtandi, has provided late-stage patients with a number of options and increased survival times by a number of months. These recent approvals are anticipated to generate strong revenues during the forecast following increasing uptake by physicians as the treatment algorithm shifts towards their first-line usage over Taxotere. Additionally, a very large late-stage pipeline is anticipated to produce a number of new market entrants which are superior to existing products. Overall, this is anticipated to drive rapid market growth from $4.1 billion in 2012 to $8.0 billion by 2019 at a CAGR of 10.1%.

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Scope

• A brief introduction to prostate cancer, including the disease’s pathogenesis, risk factors, diagnosis, staging and treatment algorithms for each stage.
• In-depth analysis of drugs available for the treatment of prostate cancer, including analyses of their safety, efficacy, treatment patterns and strengths/weaknesses. Includes a heat map comparing the drugs in terms of safety and efficacy.
• Comprehensive review of the pipeline for prostate cancer therapies, including individual analysis of a number of late-stage pipeline drugs that are likely to enter the market in the forecast period. The pipeline is analyzed on the basis of phase distribution, molecule types and molecular targets, program type.
• Additional in-depth analysis of pipeline drug clinical trials by phase, molecule type, trial size, trial duration and program failure rate analyses for each molecule type and mechanism of action.
• Multi-scenario forecast data of the market to 2019, taking into account how it will be affected by the introduction of new drugs, the expiry of key patents on current drugs and the changes in disease epidemiology across the key developed markets including the US, Japan, Germany, the UK, France, Italy and Spain.
• Discussion of the drivers and barriers for market growth.
• Discussion of the licensing and co-development deals landscape in prostate cancer, Includes an analysis of licensing deals by stage of development, molecule type and mechanism of action. Also includes an analysis of both licensing and co-development deals by year and value and network maps of licensing and co-development deals.

 Complete report is available @ http://www.rnrmarketresearch.com/prostate-cancer-therapeutics-market-to-2019-rising-prevalence-and-strong-uptake-of-recent-approvals-to-drive-robust-growth-to-2019-market-report.html. Read more on “Prostate Cancer Therapeutics Market to 2019 – Rising Prevalence and Strong Uptake of Recent Approvals to Drive Robust Growth to 2019” report below.

Reasons to Buy

• Understand the different levels of prostate cancer therapies, from early-stage prostate cacner to metastatic and castrate-resistant prostate cancer.
• Understand the vast scope and diversity of the pipeline, including which molecule types and mechanisms of action are prominent.
• Observe the trends in clinical trial duration and size amongst clinical Phases, between molecule types and mechanisms of action, and use the clinical trial failure rate analysis to assess the risk profiles of current and/or future developmental programs for prostate cancer therapeutics.
• Assess the potential clinical and commercial impact of current late-stage pipeline molecules on the prostate cancer therapeutics market.

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Zoladex, Provenge, Xgeva, Zometa Prostate Cancer Market Analysis Forecast to 2022

PharmaPoint Drug Evaluation report, “Zoladex, Provenge, Xgeva, Zometa (Prostate Cancer) – Forecast and Market Analysis to 2022″. The recent approvals of second-line metastatic castration-resistant prostate cancer (mCRPC) therapies like J&J’s Zytiga (abiraterone acetate) and Medivation/Astellas’ Xtandi (enzalutamide) will drive strong market growth over the next decade. These safe and orally administered treatments will provide safety and convenience benefits over the current standard of care, chemotherapy with docetaxel, while prolonging the overall survival of patients with mCRPC. The December 12, 2012 FDA approval of Zytiga for the added indication of chemotherapy-naïve mCRPC marks the onset of a new treatment paradigm for the disease, in which chemotherapy is relegated to second-line therapy and beyond. For patients with earlier-stage prostate cancer, androgen deprivation therapy with LHRH agonists and first-generation antiandrogens remains the standard of care for suppressing testosterone levels and temporarily controlling the disease.

Zometa Prostate Cancer Market Analysis

Novartis’ Zometa is a bisphosphonate indicated for the treatment of bone metastases in patients with CRPC, other solid tumors, and multiple myeloma. Its active ingredient, zoledronic acid, inhibits osteoclastic activity and induces apoptosis in osteoclasts, the cells responsible for bone resorption (Zometa Prescribing Information, 2012). This helps prevent the SREs that are a common symptom of bone metastases. Zometa has also been shown to inhibit the increase in osteoclast activity resulting from various stimulatory factors released by tumors. Although Zometa has been a blockbuster, worldwide patent expiries between 2012 and 2013 will open the door for generic competition and undoubtedly erode its sales (Novartis Annual Report, 2011).

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Xgeva Prostate Cancer Market Analysis

Prostate cancer frequently metastasizes to the bones, increasing the likelihood of skeletal fractures. Amgen’s Xgeva is a human Monoclonal Antibody (mAb) that binds to RANKL, a protein produced by osteoclasts involved in bone resorption, and prevents it from activating its receptor, RANK, on the osteoclast surface. This prevents the osteoclasts from breaking down bone and causing SREs (Xgeva Prescribing Information, 2010).

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Provenge Prostate Cancer Market Analysis

Dendreon’s Provenge is the first FDA-approved therapeutic cancer vaccine, and is a treatment for mCRPC. It consists of the patient’s own immune cells, which have been activated against Prostatic Acid Phosphatase (PAP), a protein found in prostate cancer cells (Provenge Prescribing Information, 2011). These activated immune cells are then infused back into the patient and induce an immune response against the prostate cancer cells.

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Zoladex Prostate Cancer Market Analysis

AstraZeneca’s Zoladex is a subcutaneous implant that delivers goserelin acetate, a synthetic analog of LHRH. It is classified as an LHRH receptor agonist (Zoladex Prescribing Information, 2010). It binds to the LHRH receptor and prevents the pituitary gland from secreting luteinizing hormone. Without luteinizing hormone, the testes do not produce testosterone. Since testosterone is known to drive the progression of prostate cancer, LHRH analogs are commonly used in ADT regimens. Zoladex is commonly used to control hormone-sensitive prostate cancer, and to maintain castrate levels of testosterone in patients with CRPC.

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Scope

- Overview of Prostate cancer, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Xgeva including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Xgeva for the top nine countries from 2012 to 2022.
- Sales information covered for the US, Japan, UK, France, Germany, Spain, Italy , Canada, and Australia

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of the competition by understanding the changing competitive landscape for Prostate cancer
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of Xgeva performance
- Obtain sales forecast for Xgeva from 2012-2022 in nine markets (US, Japan, UK, France, Germany, Spain, Italy , Canada, and Australia)

US, Canada & Australia Prostate Cancer Drug Forecast and Market Analysis to 2022

GlobalData has released its new Country report, “PharmaPoint: Prostate Cancer – US, Canada & Australia Drug Forecast and Market Analysis to 2022″. The recent approvals of second-line metastatic castration-resistant prostate cancer (mCRPC) therapies like J&J’s Zytiga (abiraterone acetate) and Medivation/Astellas’ Xtandi (enzalutamide) will drive strong market growth over the next decade. These safe and orally administered treatments will provide safety and convenience benefits over the current standard of care, chemotherapy with docetaxel, while prolonging the overall survival of patients with mCRPC. The December 12, 2012 FDA approval of Zytiga for the added indication of chemotherapy-naïve mCRPC marks the onset of a new treatment paradigm for the disease, in which chemotherapy is relegated to second-line therapy and beyond. For patients with earlier-stage prostate cancer, androgen deprivation therapy with LHRH agonists and first-generation antiandrogens remains the standard of care for suppressing testosterone levels and temporarily controlling the disease.

Prostate Cancer United States Drug Market Analysis to 2022

US prescribers widely use routine PSA screening to diagnose prostate cancer, as well as a DRE. GlobalData’s primary research shows that the majority of patients treated by urologists and medical oncologists in the US in 2011 were diagnosed or monitored using PSA screening. The diagnosis is confirmed and the cancer is staged following a TRUS-guided multiple-core needle biopsy, and any metastases are diagnosed using a bone scan or Computed Tomography (CT) scan (NCCN, 2012). Most prescribers surveyed intend to decrease their use of routine PSA screening to diagnose prostate cancer in asymptomatic patients in response to the recent USPSTF recommendation against it (see Section 5.2.2). While GlobalData predicts that the use of routine PSA screening will slightly decrease, we still believe that it will be the primary tool used in the diagnosis of prostate cancer over the forecast period, as there are currently no better, cost-effective options available.

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Prostate Cancer Canada Drug Market Analysis to 2022

In Canada, prostate cancer is diagnosed following an abnormal DRE, elevated PSA levels detected during routine screening, or a patients’ presentation with symptoms that leads to either of these tests. A suspected diagnosis of prostate cancer is confirmed by TRUS-guided multiple core needle biopsies, and bone metastases are detected using a CT scan or bone scan. The uptake of routine PSA screening has been high in Canada, but some Canadian physicians surveyed by GlobalData reported that they plan to decrease their use of routine screening in response to the recent USPSTF recommendation against it (Baade et al., 2009).

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Prostate Cancer Australia Drug Market Analysis to 2022

In Australia, prostate cancer is diagnosed following a patient’s presentation with symptoms, elevated PSA levels as a result of routine screening, or an abnormal DRE. The diagnosis is confirmed after multiple core needle biopsies or TRUS, and bone metastases are detected by CT or bone scan. Routine PSA screening is more commonly used in Australia compared with the 5EU, but less frequently than in the US (Baade et al., 2009).

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Scope

- Overview of RA, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on the key drugs in the US including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for the top drugs in the US from 2012 to 2022.
- Analysis of the impact of key events as well the drivers and restraints affecting the US Prostate cancer market.

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of the competition by understanding the changing competitive landscape for Prostate cancer
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of Prostate cancer drug performance in the US
- Obtain sales forecast from 2012-2022 in The US